Senior Director/Director Business Development (oncology)

Company: ORIC Pharmaceuticals
Location: South San Francisco
Posted on: February 18, 2026

Job Description:

Job Description Job Description Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com, and follow us on X or LinkedIn. The Director/Senior Director, Business Development, is a strategic leader responsible for driving growth, forging key partnerships, and advancing the company’s oncology pipeline. This broad role requires experience in oncology drug development, strong scientific and commercial acumen, and the ability to influence at all levels both internally and externally. The Director/Senior Director, Business Development, will report directly to ORIC’s Chief Business Officer and be involved in all aspects of business development, including competitive intelligence, alliance management, search and evaluation, in-licensing, out-licensing, and commercial assessments. The Director/Senior Director, Business Development, is expected to work collaboratively across functions within the organization, represent ORIC to external partners, and play a pivotal role in executing our corporate strategy and mission in oncology. Job Description • Develop and maintain a comprehensive understanding of the company’s oncology pipeline, R&D capabilities, and strategic objectives. • Lead competitive intelligence and therapeutic area landscape assessments in prostate cancer and non-small cell lung cancer, providing actionable insights to cross-functional stakeholders. • Build and manage strategic alliances with current and prospective partners in the oncology space, ensuring alignment with corporate goals. • Stay abreast of industry trends and competitor activities in oncology to inform business development strategy. • Support executive leadership in strategic planning, forecasting, and the development of presentation materials for internal and external audiences. • Identify, evaluate, and recommend new business development opportunities, including in-licensing, out-licensing, partnerships, and M&A, with a focus on oncology assets. • Oversee due diligence processes, including scientific, clinical, market, and financial analyses to support business cases for new oncology opportunities. Qualifications • Bachelor’s degree in life sciences required; advanced degree (MBA, MS, MD, or PhD) preferred. • 8–10 years of biotechnology or pharmaceutical industry experience, with a proven track record in oncology business development, competitive intelligence, market research, and/or strategic partnerships. • Excellent communication, presentation, and relationship-building abilities. • Strong analytical, financial modeling, and project management skills. Key Competencies • Commercial, clinical and scientific acumen in oncology • Strategic thinking and problem-solving in oncology drug development • Influencing and negotiation with scientific, clinical and commercial partners • Cross-functional collaboration (R&D, clinical, regulatory, commercial) Oncology-Specific Focus Areas • Deep understanding of oncology therapeutic landscapes. Experience with prostate cancer and/or non-small cell lung cancer desired. • Experience with interpreting scientific data, analyzing clinical trial designs, understanding regulatory frameworks, and evaluating commercial opportunities for oncology therapies. • Ability to assess and communicate the value proposition of oncology programs to internal and external stakeholders. Additional Information The anticipated salary range for candidates who will work in our South San Francisco location is between $250,000–$285,000 for the Senior Director and between $210,000-$260,000 for the Director. The final salary offered to a successful candidate will be dependent on several factors that may include, title, type and length of experience within the role, type and length of experience within the industry, education, geography, and other job-related factors. ORIC Pharmaceuticals, Inc. is an equal opportunity employer. ORIC does not discriminate based on race, color, religion, gender, sexual orientation, gender identity, age, national origin, disability status, protected veteran status, or any other legally protected characteristics.

Keywords: ORIC Pharmaceuticals, San Ramon , Senior Director/Director Business Development (oncology), Science, Research & Development , South San Francisco, California